Tablets – 5 mg
Diazepam is a long – acting benzodiazepinic preparation. It exerts an anxiolytic, hypno – sedative (hypnotic and sedative), muscle relaxant and anticonvulsant action through the specific benzodiazepinic receptors, the major part of which are found in the lymbic system, hypotalamus, cerebellum and corpus striatum. These receptors and the gamma – aminobutyric acid (GABA) receptors form an anatomical and functional unit. After diazepam is bound with a receptor, then the GABA transmission and the central nervous system inhibition is potentiated. The consequences are manifested with an anticonvulsant and muscle relaxant action. The stimulatory action of serotonine, noradrenaline and acetylcholine neurotransmitters is reduced, because of the increased action of GABA and as a consequence, the anxiolytic, hypnotic and sedative action of diazepam is potentiated.
Diazepam is used as follows:
Tablets: anxiety conditions, insomnia, muscle spasms, acute alcohol withdrawal syndrome.
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